| dc.description.abstract | ABSTRACT: In this study, 91 participants were randomly selected from the Center for Diabetes and Endocrinology Alkoms-Libya. Then, the participants were split into two groups: the 66 patients and the 25 participants in the control group. All the special measurements were taken for the patient and control groups, such as: fasting blood sugar, HbA1c, serum amylase, urine amylase, blood and urine creatinine, the amylase creatinine clearance rate was calculated by a certain equation. Safety evaluations included vital signs of laboratory parameters.
The mean and standard error for all cases in this investigation were as follows for the following measurements: fasting blood sugar, HbA1c, serum amylase, urine amylase, and amylase creatinine clearance as follows: 148.38 ± 8.43 mg/dl, 6.31 ± 0.22%, 46.29 ± 4.94 U/l, 176.48 ± 17.95U/l, 1.15 ± 0.16% respectively. When comparing the mean and standard error between patients and control for: fasting blood sugar, HbA1c, serum amylase, urine amylase, amylase creatinine clearance as follows: 86.08±1.77 mg/dl, 4.61±0.06%, 37.48±4.94U/l, 143.16±18.51U/l, 1.37±0.19% respectively, Patients were 171.98±10.20mg/dl, 6.95±0.26%, 49.62±6.53U/l, 189.11±23.63U/l, 1.07±0.21% respectively, where the group of patients was higher than control except for amylase creatinine clearance was higher in control group. The comparisons in the different blood clinical parameters of the two groups, there were no significant relationships except for a relationship between the disease and serum amylase. The value of p-value = 0.05, which means that a relationship is at a significant level of 5%. There was also a relationship between fasting blood sugar and serum amylase, where p-value = 0.04.
According to the results of this study, low levels of amylase and low levels of amylase creatinine clearance occur in the absence of pancreatitis, high levels of amylase increase the likelihood of developing pancreatitis, and none of the participants had Insulin Dependent Diabetes Mellitus. There was an increase in serum and urine amylase levels in diabetics compared to control, after collecting the data and analyzing it. It is obvious that there is an increase in amylase level in serum, urine amylase, except for amylase level where it is decreased, which indicate that the high blood sugar is connected to the enzyme amylase. | en_US |
